TY - CHAP M1 - Book, Section TI - The Principle of Intention to Treat and Ambiguous Dropouts A1 - Briel, Matthias A1 - Montori, Victor M. A1 - Durieux, Pierre A1 - Devereaux, PJ A1 - Guyatt, Gordon A2 - Guyatt, Gordon A2 - Rennie, Drummond A2 - Meade, Maureen O. A2 - Cook, Deborah J. PY - 2015 T2 - Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed AB - Reports of randomized clinical trials (RCTs) frequently refer to “dropouts” from the study. Unfortunately, RCT authors may be referring to 1 of 2 different phenomena. The first phenomenon includes study participants who no longer comply with the intervention (typically the experimental treatment and typically a drug) but who are willing to continue with follow-up for the outcome events of interest. The second phenomenon includes study participants who, for a number of possible reasons (eg, moved away or refused further participation), are no longer available and are thus lost to follow-up. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/25 UR - jamaevidence.mhmedical.com/content.aspx?aid=1183876027 ER -