RT Book, Section
A1 Briel, Matthias
A1 Montori, Victor M.
A1 Durieux, Pierre
A1 Devereaux, PJ
A1 Guyatt, Gordon
A2 Guyatt, Gordon
A2 Rennie, Drummond
A2 Meade, Maureen O.
A2 Cook, Deborah J.
SR Print(0)
ID 1183876027
T1 The Principle of Intention to Treat and Ambiguous Dropouts
T2 Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-179071-0
LK jamaevidence.mhmedical.com/content.aspx?aid=1183876027
RD 2024/04/19
AB Reports  of  randomized  clinical  trials  (RCTs)  frequently  refer  to  “dropouts”  from  the  study.  Unfortunately,  RCT  authors  may  be  referring  to  1  of  2  different  phenomena.  The  first  phenomenon  includes  study  participants  who  no  longer  comply  with  the  intervention  (typically  the  experimental  treatment  and  typically  a  drug)  but  who  are  willing  to  continue  with  follow-up  for  the  outcome  events  of  interest.  The  second  phenomenon  includes  study  participants  who,  for  a  number  of  possible  reasons  (eg,  moved  away  or  refused  further  participation),  are  no  longer  available  and  are  thus  lost  to  follow-up.