RT Book, Section
A1 Richardson, W. Scott
A1 Wilson, Mark C.
A1 McGinn, Thomas
A2 Guyatt, Gordon
A2 Rennie, Drummond
A2 Meade, Maureen O.
A2 Cook, Deborah J.
SR Print(0)
ID 1183877063
T1 Differential Diagnosis
T2 Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-179071-0
LK jamaevidence.mhmedical.com/content.aspx?aid=1183877063
RD 2024/04/19
AB CLINICAL  SCENARIOYour  patient  is  a  78-year-old  man  who,  at  today's  routine  visit  for  the  follow-up  of  his  longstanding  hypertension,  is  surprised  to  be  told  that  his  weight  has  decreased  10  kg  since  his  last  visit  6  months  ago.  He  reports  eating  less,  with  little  appetite  but  no  food-related  symptoms.  He  takes  a  diuretic  for  his  hypertension,  with  no  change  in  dose  for  more  than  a  year,  and  uses  acetaminophen  for  occasional  knee  pain  and  stiffness.  He  stopped  smoking  11  years  ago,  and  he  stopped  drinking  alcohol  4  decades  ago.  His  examination  reveals  him  to  be  extremely  thin  but  provides  no  localizing  clues.  His  initial  blood  and  urine  test  results  are  normal.You  review  the  long  list  of  the  possible  causes  of  involuntary  weight  loss,  yet  you  realize  that  an  immediate  exhaustive  search  for  all  possibilities  is  not  sensible.  Instead,  you  will  seek  information  about  the  causes  of  involuntary  weight  loss  that  are  common  and  most  plausible  in  this  patient.