Skip to Main Content

Welcome to JAMAevidence

Evidence-based medicine (EBM) integrates the best available evidence with clinical experience that allows clinicians to recommend, and their patients to make, informed choices consistent with their values. JAMAevidence helps decision makers identify the best available evidence by providing guides to the systematic consideration of the validity, importance, and applicability of claims about the assessment of health problems and the outcomes of health care.
JAMAEvidence features on a personal computer, smart phone and tablet


Cover for Users' Guides to the Medical Literature

Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd Edition

Now in its third edition, the Users' Guides is the centerpiece of EBM theory on JAMAevidence.
Online Features
Chapters are complimented with Education Guide slide sets, audio summaries, calculators, and critical appraisal and information cycle worksheets.
You may purchase a print copy of this textbook here.
Cover for The Rational Clinical Examination

The Rational Clinical Examination: Evidence-Based Clinical Diagnosis

Available for the first time in a single compilation, The Rational Clinical Examination articles and updates turn EBM theory into practice via topically organized chapters.
Make the Diagnosis
These sections of The Rational Clinical Examination summarize current evidence for clinical evaluation of a topic; compiling the evidence to make a diagnosis; and applying the evidence.
You may purchase a print copy of this textbook here.
Cover for JAMA Guide to Statistics and Methods

JAMA Guide to Statistics and Methods

Available for the first time, this collection of brief example-based summaries of common and new statistical and methodologic concepts helps clinicians understand and interpret statistics and methods reported in research articles and determine relevancy for their clinical practice.
Online Features
Chapters are complimented by hyperlinked definitions of statistical and methodologic terms, Education Guide slide sets, and audio summaries.
You may purchase a print copy of this textbook here.
Cover for Care at the Close of Life

Care at the Close of Life: Evidence and Experience

Part of the acclaimed JAMAevidence series, this groundbreaking resource offers expert guidance and carefully reviewed evidence on caring for patients at the end of life. It focuses on practical, real-world issues faced by primary care physicians and covers topics from communication issues to disease management to clinician self-care.
Includes a self-assessment quiz and review questions in each chapter to ensure mastery of key concepts.
You may purchase a print copy of this textbook here.

Useful Tools

Icon for Education Guides

Education Guides

JAMAevidence offers a robust library of PowerPoint slide sets aimed at instruction and learning of EBM concepts. They are linked to related content and are available through search. Sample Education Guides from Users’ Guides to the Medical Literature, 3e (PowerPoint download) , The Rational Clinical Examination (PowerPoint download), and Care at the Close of Life: Evidence and Experience (PowerPoint download) are available for free.
Icon for Glossary


Browse more than 900 EBM terms and definitions from the global navigation button. Terms are linked to pop-up definitions inside book content and are also available via search.
Icon for Calculators


Calculators are functional, interactive tools designed to enhance the user's understanding of statistical and mathematical relationships in EBM. They are available via the global navigation button as well as through search. Review the Risk Reduction Calculator for free.
Screenshot of Worksheets


Worksheets are interactive applications that provide users with a framework for studying EBM concepts. They are comprised of textual instructions as well as open, editable fields where learners can respond to instructions and prompts. For example, a worksheet may help the user organize notes on clinical literature in a particular patient case. Two types of worksheets are available on JAMAevidence: critical appraisal guides and information cycle problem-solving aids. They may be printed, edited, and saved to a user's personal profile. Users fill in a rich-text editing box with a formatting toolbar and spellcheck.

Critical Appraisal

Critical appraisal forms help users learn to evaluate research findings by considering validity, importance, and applicability of results. Notes entered into these worksheets by individually identified users are stored for later access and revision. Critical appraisal forms are available via their specific locations in the Users' Guides text, as well as on a user's My Access account page.
Icon representing information cycle

Information Cycle

Information cycle forms allow users to explore the "5 A's" of EBM practice: Assess the information, Ask specific questions, Acquire evidence, Appraise the data for validity, Apply evidence to patient care. Notes entered into these worksheets are stored for later access and revision. Information cycle forms are available via their specific locations in the Users' Guides text, as well as on a user's My Access account page.

Other Features

Screenshot of MyAccess profile dashboard

My Access account

Formerly a My JAMAevidence account, a My Access account provides users with quick access to their most recent saved content: worksheets, images, and tables and allows users to take self-assessment quizzes and to edit their profile.

This Week's JAMA RSS Feed

Keep up to date with this weekly feed of featured JAMA articles.

Compiled Clinical Scenarios

A single, seamless clinical case has been created for both books by merging the intra-chapter Scenario sections together. This merged view is accessible via the home page as well as inside each chapter.
Icon for Audio Podcast feature

Audio Files

Audio files of key EBM concepts have been recorded by subject-matter experts. Syndication and sample audio are accessible via the home page, a designated Audio page (available from global navigation), and in search results.
Icon representing Authors

Editors and Authors

Read more about the Editors and Authors of JAMAevidence.
Icon representing subscriptions


Institutions: Please contact our sales office for pricing or for more information.
Individuals: See pricing and subscribe details.
Icon representing monthly updates

Monthly Updating

As current EBM concepts and clinical literature come to the fore, the JAMAevidence content set will be refreshed on a monthly basis. The site will be enhanced with additional multimedia files, new textbook material, and timely updates.
Icon representing additional information for librarians

Additional Information for Librarians

JAMAevidence offers retrievable institutional user statistics and MARC 21 records.  JAMAevidence also offers flexible access for both in-network and remote users via IP authentication, Athens authentication, referral URL, and/or user name and password. For additional resources and promotional materials, visit our Access User Center.