Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Related Content +++ ORGANIZATIONAL STRUCTURE OF THIS BOOK ++Table Graphic Jump LocationView Table||Download (.pdf) Interventional Studies Trial Strategy and Design Enrollment, Allocation of Treatment, and Ethics Measurement Outcome and Analysis and Interpretation of Results Application of Results Noninferiority Trials Dose-Finding Trials Pragmatic Trials Cluster Randomized Trials The Stepped-Wedge Clinical Trial Sample Size Calculation for a Hypothesis Test Minimal Clinically Important Difference Randomization in Clinical Trials Equipoise in Research Time-to-Event Analysis The “Utility” in Composite Outcome Measures Missing Data The Intention-to-Treat Principle Analyzing Repeated Measurements Using Mixed Models Logistic Regression Logistic Regression Diagnostics Number Needed to Treat Multiple Comparison Procedures Gatekeeping Strategies for Avoiding False-Positive Results in Clinical Trials With Many Comparisons Multiple Imputation Interpretation of Clinical Trials That Stopped Early Bayesian Analysis Decision Curve Analysis Methods for Evaluating Changes in Health Care Policy—The Difference-in-Differences Approach Observational Studies Study Strategy and Design Assessment of Risk Factors and Exposures Measurement Outcome and Analysis and Interpretation of Results Application of Results Case-Control Studies Meta-analyses Can Be Credible and Useful Mendelian Randomization Using the E-Value to Assess the Potential Effect of Unmeasured Confounding in Observational Studies Confounding by Indication in Clinical Research Mediation Analysis Odds Ratios—Current Best Practice and Use Marginal Effects—Quantifying the Effect of Changes in Risk Factors in Logistic Regression Models Adjusting for Covariates Treatment Effects in Multicenter Randomized Clinical Trials The Propensity Score Using Free-Response Receiver Operating Characteristic Curves to Assess the Accuracy of Machine Diagnosis of Cancer Random-Effects Meta-analysis Bayesian Hierarchical Models Evaluating Discrimination of Risk Prediction Models Overview of Cost-effectiveness Analysis Choosing a Time Horizon in Cost and Cost-effectiveness Analysis On Deep Learning for Medical Image Analysis Practical Guide to Data Sets 13 Articles Your Access profile is currently affiliated with [InstitutionA] and is in the process of switching affiliations to [InstitutionB]. Please select how you would like to proceed. Keep the current affiliation with [InstitutionA] and continue with the Access profile sign in process Switch affiliation to [InstitutionB] and continue with the Access profile sign in process Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Error: Incorrect UserName or Password Username Error: Please enter User Name Password Error: Please enter Password Sign in Forgot Password? Forgot Username? Download the Access App: iOS | Android Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free profile for additional features.