TY - CHAP M1 - Book, Section TI - Composite End Points A1 - Ferreira-González, Ignacio A1 - Montori, Victor M. A1 - Busse, Jason W. A1 - Schünemann, Holger J. A1 - Jaeschke, Roman A1 - Deveraux, PJ A1 - Permanyer-Miralda, Gaietà A1 - Guyatt, Gordon A2 - Guyatt, Gordon A2 - Rennie, Drummond A2 - Meade, Maureen O. A2 - Cook, Deborah J. PY - 2015 T2 - Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed AB - CLINICAL SCENARIOYou are an internist seeing a 65-year-old man with stress test–documented angina who—despite taking carefully titrated β-blockers, nitrates, aspirin, an angiotensin-converting enzyme (ACE) inhibitor, and a statin—is substantially restricted in his activities. The patient undergoes coronary angiography, which reveals 3-vessel severe coronary disease. You suggest to him the possibility of surgical revascularization with coronary artery bypass grafting (CABG). The patient expresses reluctance to undergo such an invasive procedure, and he asks if there is a less aggressive approach that might be almost as effective. You consider the possibility of a percutaneous coronary intervention (PCI) as an alternative. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/06 UR - jamaevidence.mhmedical.com/content.aspx?aid=1183876406 ER -