TY - CHAP M1 - Book, Section TI - Differential Diagnosis A1 - Richardson, W. Scott A1 - Wilson, Mark C. A1 - McGinn, Thomas A2 - Guyatt, Gordon A2 - Rennie, Drummond A2 - Meade, Maureen O. A2 - Cook, Deborah J. PY - 2015 T2 - Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed AB - CLINICAL SCENARIOYour patient is a 78-year-old man who, at today's routine visit for the follow-up of his longstanding hypertension, is surprised to be told that his weight has decreased 10 kg since his last visit 6 months ago. He reports eating less, with little appetite but no food-related symptoms. He takes a diuretic for his hypertension, with no change in dose for more than a year, and uses acetaminophen for occasional knee pain and stiffness. He stopped smoking 11 years ago, and he stopped drinking alcohol 4 decades ago. His examination reveals him to be extremely thin but provides no localizing clues. His initial blood and urine test results are normal.You review the long list of the possible causes of involuntary weight loss, yet you realize that an immediate exhaustive search for all possibilities is not sensible. Instead, you will seek information about the causes of involuntary weight loss that are common and most plausible in this patient. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/09/08 UR - jamaevidence.mhmedical.com/content.aspx?aid=1183877063 ER -