TY  - CHAP
M1  - Book, Section
TI  - Understanding Class Effects
A1  - Mills, Edward J.
A1  - Gardner, David
A1  - Thorlund, Kristian
A1  - Briel, Matthias
A1  - Bucher, Heiner C.
A1  - Bryan, Stirling
A1  - Hutton, Brian
A1  - Guyatt, Gordon
A2  - Guyatt, Gordon
A2  - Rennie, Drummond
A2  - Meade, Maureen O.
A2  - Cook, Deborah J.
Y1  - 2015
N1  - 
T2  - Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd ed
AB  - CLINICAL  SCENARIOAs  a  cost-cutting  strategy,  your  hospital's  Phar—macy  and  Therapeutics  Committee  is  recommending  a  strategy  wherein  drugs  within  the  same  class  can  be  substituted  at  the  level  of  the  pharmacy  for  the  generic  or  least  costly  within-class  option.  As  a  physician  dealing  predominantly  with  cardiovascular  prevention,  this  would  have  important  implications  on  your  practice.  Your  clinical  team  questions  the  new  policy,  and  several  members  argue  that  assuming  that  drugs  with  a  similar  chemical  structure  exert  similar  effect  on  patient-important  outcomes  without  direct  evidence  is  misguided.  Statins  are  the  most  widely  prescribed  drug  within  your  practice,  and  you  wonder  whether  there  is  a  therapeutic  class  effect  for  statins.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - jamaevidence.mhmedical.com/content.aspx?aid=1183878502
ER  -