RT Book, Section A1 DeMets, David L. A1 Psaty, Bruce M. A1 Fleming, Thomas R. A2 Livingston, Edward H. A2 Lewis, Roger J. SR Print(0) ID 1209176609 T1 When Can Intermediate Outcomes Be Used as Surrogate Outcomes? T2 JAMA Guide to Statistics and Methods YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781260455328 LK jamaevidence.mhmedical.com/content.aspx?aid=1209176609 RD 2024/10/06 AB This JAMA Guide to Statistics and Methods reviews how and under what conditions surrogate outcomes can replace patient-centered outcomes in randomized trials and stresses the importance of properly validating outcomes as surrogates for direct measures of patient experiences.