Skip to Main Content

Audio

A monthly series of discussions of core issues in evidence-based medicine by leading practitioners in the field.

Recorded and produced by JAMA editors for JAMAevidence, an innovative online resource for using evidence to improve care.

Listen on Apple Podcasts

...or paste the following RSS address into your podcast app:

http://jamaevidenceusersguidemedicalliterature.jamanetwork.libsynpro.com/rss

http://jamaevidencerationalclinicalexamination.jamanetwork.libsynpro.com/rss

http://jamaevidencejamaguidetostatisticsandmethods.jamanetwork.libsynpro.com/rss

http://jamaevidencecareatthecloseoflife.jamanetwork.libsynpro.com/rss

Sections

Introduction to JAMAevidence

Users' Guides to the Medical Literature

The Rational Clinical Examination

JAMA Guide to Statistics and Methods

Care at the Close of Life

Cover Image

Introduction to JAMAevidence: Drummond Rennie, MD, discusses the impetus and authorship behind JAMAevidence, which provides fundamental tools for dealing with the medical literature and making clinical diagnoses.

By Drummond Rennie, MD

8:02

Cover Image

Per Olav Vandvik, MD, PhD, discusses how to apply the GRADE approach when evaluating the strength of recommendations to help clinicians move from evidence to action.

By Per Olav Vandvik, MD, PhD

15:55

Cover Image

M. Hassan Murad, MD, discusses evidence quality, the GRADE approach, and the Users’ Guide to understanding and applying the results of a systematic review.

By M.Hassan Murad, MD

16:27

Cover Image

M. Hassan Murad, MD, discusses the Users’ Guide on fixed-effects and random-effects models.

By M.Hassan Murad, MD

20:32

Cover Image

Romina Brignardello-Petersen, DDS, MSc, and Gordon Guyatt, MD, MSc, discuss the Users’ Guide on how to interpret and use a clinical practice guideline or recommendation.

By Romina Brignardello-Petersen, DDS, MSc

32:29

Cover Image

Thomas Agoritsas, MD, PhD, discusses the Users’ Guide to adjusted analyses in studies addressing therapy and harm.

By Thomas Agoritsas, MD, PhD

17:23

Cover Image

Reem A. Mustafa, MD, discusses the Users’ Guide to spectrum bias.

By Reem A. Mustafa, MD

14:08

Cover Image

Ana Carolina Alba, MD, PhD, discusses the Users’ Guide on discrimination and calibration of clinical prediction models.

By Ana Carolina Alba, MD, PhD

16:47

Cover Image

Edward J. Mills, PhD, and Jay J. H. Park, PhD, discuss the Users’ Guide on how to use and interpret the results of a platform trial.

By Edward J. Mills, PhD

25:44

Cover Image

Thomas McGinn, MD, MPH, discusses the Users’ Guide on measuring agreement beyond chance.

By Thomas McGinn, MD, MPH

15:01

Cover Image

Roman Jaeschke, MD, MSc, FRCPC, discusses the Users’ Guide on correlation and regression.

By Roman Jaeschke, MD, MSc, FRCPC

15:47

Cover Image

Paul Moayyedi, BSc, MBChB, PhD, MPH, discusses the Users’ Guide for economic analysis.

By Paul Moayyedi, BSc, MBChB, PhD, MPH

25:44

Cover Image

Victor M. Montori, MD, MSc, discusses the Users’ Guide for misleading presentations of clinical trial results.

By Victor M. Montori, MD, MSc

31:28

Cover Image

Anne M. Holbrook, MD, PharmD, MSc, FRCPC, explains how to understand and assess surrogate outcomes when reviewing the medical literature.

By Anne M Holbrook, MD, PharmD, MSc, FRCPC

17:25

Cover Image

Yun Liu, PhD, discusses how to read an article that uses machine learning.

By Yun Liu, PhD

25:28

Cover Image

Victor M. Montori, MD, MSc, discusses decision making and the patient.

By Victor Montori, MD, MSc

20:46

Cover Image

Thomas Agoritsas, MD, PhD, discusses how to apply results to individual patients.

By Thomas Agoritsas, MD, PhD

19:17

Cover Image

Gordon Guyatt, MD, discusses how to use a subgroup analysis.

By Gordon Guyatt, MD

09:57

Cover Image

Gordon Guyatt, MD, discusses composite end points.

By Gordon Guyatt, MD

23:32

Cover Image

W. Scott Richardson, MD, discusses differential diagnosis.

By W. Scott Richardson, MD

24:48

Cover Image

John Attia, MD, PhD, discusses how to use an article about genetic association.

By John Attia, MD, PhD

15:04

Cover Image

George Tomlinson, PhD, discusses how to use an article about hypothesis testing and appropriate interpretation of P values.

By George Tomlinson, PhD

16:14

Cover Image

Eddy Fan, MD, PhD, discusses how to use an article about quality improvement.

By Eddy Fan, MD, PhD

10:51

Cover Image

Gordon Guyatt, MD, discusses network meta-analysis.

By Gordon Guyatt, MD

09:03

Cover Image

Matthias Briel, MD, discusses the principle of intention to treat and ambiguous dropouts.

By Matthias Briel, MD

19:25

Cover Image

Evidence-Based Medicine and the Theory of Knowledge: Interview With Dr Gordon Guyatt

By Gordon Guyatt, MD

18:21

Cover Image

Recommendations About Screening: Interview With Gemma Louise Jacklyn

By Gemma Louise, BAppSc, MPH(Hons)

33:43

Cover Image

How to Use a Noniferiority Trial: Interview With Dr Gordon Guyatt

By Gordon Guyatt, MD

21:26

Cover Image

Clinical Prediction Rules: Interview With Dr Thomas G. McGinn

By Dr Thomas G. McGinn and Dr Edward Livingston

6:55

Cover Image

The Process of a Systematic Review and Meta-analysis: M. Hassan Murad, MD, MPH, discusses the process of a systematic review and meta-analysis.

By Dr M Hassan Murad and Dr Edward Livingston

14:17

Cover Image

The Origin of Evidence-Based Medicine and the Users' Guides to the Medical Literature: Gordon Guyatt, MD, MSc, explains the origin of the term "evidence-based medicine" and describes the Users' Guides to the Medical Literature and the benefits of applying the medical literature to clinical practice.

By Gordon Guyatt, MD, MSc

19:35

Cover Image

Applying Evidence-Based Practice: Robert Hayward, MD, explains how clinicians can apply evidence-based medicine to their practices.

By Robert Hayward, MD

8:08

Cover Image

The 5As of the Health Information Cycle: Robert Hayward, MD, defines the 5As of the health information cycle and helps learners understand the process.

By Robert Hayward, MD

10:46

Cover Image

What is the Question? Gordon Guyatt, MD, MSc, discusses "Chapter 3: What Is the Question?" from the Users' Guides to the Medical Literature.

By Gordon Guyatt, MD, MSc

9:04

Cover Image

Therapy (Randomized Trials): Gordon Guyatt, MD, MSc, discusses "Chapter 6: Therapy (Randomized Trials)" from the Users' Guides to the Medical Literature.

By Gordon Guyatt, MD, MSc

15:05

Cover Image

The Process of Diagnosis: Gordon Guyatt, MD, MSc, discusses "Chapter 14: The Process of Diagnosis" from the Users' Guides to the Medical Literature.

By Gordon Guyatt, MD, MSc

10:51

Cover Image

Summarizing the Evidence: Gordon Guyatt, MD, discusses "Chapter 19: Summarizing the Evidence" from the Users' Guides to the Medical Literature.

By Gordon Guyatt, MD

10:39

Cover Image

Finding the Evidence: Ann McKibbon, MLS, PhD, discusses "Chapter 4: Finding the Evidence" from the Users' Guides to the Medical Literature.

By Ann McKibbon, MLS, PhD

9:00

Cover Image

Randomized Trials Stopped Early for Benefit: Victor Montori, MD, discusses randomized trials that are stopped early for benefit.

By Victor Montori, MD

7:23

Cover Image

N-of-1 Randomized Controlled Trials: Gordon Guyatt, MD, discusses n-of-1 randomized controlled trials.

By Gordon Guyatt, MD

14:57

Cover Image

Measuring Patients' Experience: Toshi A. Furukawa, MD, PhD, discusses measuring patients' experience.

By Toshi A. Furukawa, MD, PhD

8:57

Cover Image

Does Treatment Lower Risk? Roman Jaeschke, MD, MSc, discusses whether treatment lowers risk.

By Roman Jaeschke, MD, MSc

10:16

Cover Image

Harm (Observational Studies): Mitchell Levine, MD, MSc, discusses harm (observational studies).

By Mitchell Levine, MD

7:52

Cover Image

Philosophy of evidence-based medicine: Victor Montori, MD, discusses the philosophy of evidence-based medicine.

By Victor Montori, MD

19:34

Cover Image

Prognosis: Adrienne Randolph, MD, MSc, discusses prognosis.

By Adrienne Randolph, MD, MSc

12:40

Cover Image

Confidence Intervals: Gordon Guyatt, MD, discusses confidence intervals.

By Gordon Guyatt, MD

15:56

Cover Image

Diagnostic Tests: Toshi A. Furukawa, MD, PhD, discusses diagnostic tests.

By Toshi A. Furukawa, MD, PhD

16:10

Cover Image

Surprising Results of Randomized Trials: Gordon Guyatt, MD, surprising results of randomized trials.

By Gordon Guyatt, MD

10:38

Cover Image

Why Study Results Mislead: Gordon Guyatt, MD, discusses bias, random error, and why study results sometimes mislead.

By Gordon Guyatt, MD

7:34

Cover Image

Understanding the Results: More About Odds Ratios: Gordon Guyatt, MD, discusses odd ratios.

By Gordon Guyatt, MD

10:29

Cover Image

James T. Nugent, MD, MPH, discusses the clinical examination for identifying secondary hypertension in children with high blood pressure.

By James T. Nugent, MD, MPH

19:32

Cover Image

Davin Johnson, MD, discusses the clinical examination for diagnosing acute conjunctivitis and assessing whether it is bacterial or viral in origin.

By Davin J. Johnson, MD

19:44

Cover Image

Anthony J. Viera, MD, MPH, discusses the clinical examination for hypertension in adults.

By Anthony J. Viera, MD, MPH

12:40

Cover Image

David Metcalfe, PhD, MRCP, MRCS, MRCEM, discusses the clinical examination for hip osteoarthritis.

By David Metcalfe, PhD, MRCP, MRCS, MRCEM

11:53

Cover Image

Edward Etchells, MD, discusses the clinical examination for cardiac syncope.

By Edward Etchells, MD

16:36

Cover Image

Michael E. Detsky, MD, MSHP, discusses the clinical examination for difficult intubation.

By Michael E. Detsky, MD, MSHP

15:42

Cover Image

Charles J. Gerardo, MD, MHS, discusses the clinical examination for severe envenomation after snakebite.

By Charles J. Gerardo, MD, MHS

11:21

Cover Image

David Meier, MD, and Tinh-Hai Collet, MD, discuss the clinical examination for acute mountain sickness with David L. Simel, MD.

By Meier David, MD

16:01

Cover Image

Evan Wood, MD, PhD, FRCPC, discusses the clinical examination for severe alcohol withdrawal syndrome.

By Evan Wood, MD, PhD, FRCPC

19:34

Cover Image

Sonal N. Shah, MD, MPH, discusses the clinical examination for childhood pneumonia.

By Sonal N. Shah, MD, MPH

09:35

Cover Image

Peter Bentzer, MD, PhD, discusses the clinical examination for fluid responsiveness in hemodynamically unstable patients.

By Peter Bentzer, MD, PhD

14:12

Cover Image

Evan Wood, MD, PhD, FRCPC, discusses the clinical examination for early HIV infection.

By Evan Wood, MD, PhD, FRCPC

15:03

Cover Image

Sophiya Benjamin, MBBS, discusses the clinical examination for generalized anxiety or panic disorder.

By Sophiya Benjamin, MBBS

13:20

Cover Image

Cynthia A. Moylan, MD, discusses the clinical examination for liver disease and cirrhosis.

By Cynthia A. Moylan, MD

20:13

Cover Image

Job Hermans, MD, MSc, discusses the clinical examination for rotator cuff disease.

By Job Hermans, MD, MSc

09:05

Cover Image

Kathryn A. Myers, MD, discusses the clinical examination for obstructive sleep apnea.

By Kathryn A. = Myers, MD

12:07

Cover Image

Bryan Coburn, MD, PhD, discusses the clinical examination for bacteremia.

By Bryan Coburn, MD, PhD

12:21

Cover Image

Delan Jinapriya, MD, FRCSC, discusses the clinical examination for primary open-angle glaucoma.

By Delan Jinapriya, MD, FRCSC

13:22

Cover Image

Edward H. Livingston, MD, discusses the clinical examination for mononucleosis.

By Edward H. Livingston, MD

32:48

Cover Image

Does This Women Have an Ectopic Pregnancy? Interview With Dr John R. Crochet

By John R. Crochet, MD

8:08

Cover Image

Will Neuroimaging Reveal a Severe Intracranial Injury in This Adult With Minor Head Trauma? Interview With Joshua S. Easter, MD, MSc

By Joshua S. Easter, MD, MSc

24:55

Cover Image

Does This Adult Patient Have Blunt Intra-abdominal Injury? Interview With Daniel K. Nishijima, MD, MAS

By Daniel K. Nishijima, MD, MAS

7:30

Cover Image

Understanding How to Use Likelihood Ratios in Clinical Practice: A Conversation With the Rational Clinical Examination Editor, David L. Simel, MD, MHS

By David L. Simel, MD, MHS

14:47

Cover Image

Acute Coronary Syndrome: Interview With Dr Alexander C. Fanaroff

By Alexander C. Fanaroff, MD

17:29

Cover Image

Does This Older Adult With Lower Extremity Pain Have the Clinical Syndrome of Lumbar Spinal Stenosis?

By Pradeep Suri, MD

13:10

Cover Image

Does This Patient Have Posttraumatic Stress Disorder? Interview With Dr Michele R. Spoont

By Michele R. Spoont, PhD

23:08

Cover Image

Malaria: Interview With Dr Steve M. Taylor

By Dr Steve M. Taylor and Dr Edward Livingston

29:43

Cover Image

F. Douglas Srygley, MD, and Dr David L. Simel, MD, MHS, discuss the clinical examination for upper gastrointestinal bleed.

By Dr F. Douglas Srygley, Dr David L. Simel, and Dr Edward Livingston

32:39

Cover Image

Nadia A. Khan, MD, MSc, discusses the clinical examination for peripheral arterial disease.

By Dr Nadia A. Khan and Dr Edward Livingston

15:43

Cover Image

Abnormal Central Venous Pressure: David L. Simel, MD, MHS, discusses the clinical examination for abnormal central venous pressure.

By David L. Simel, MD, MHS

7:05

Cover Image

Does This Patient Have an Alcohol Problem?: Sheri A. Keitz, MD, PhD, discusses the rational clinical examination for alcohol abuse.

By Sheri A. Keitz, MD, PhD

11:42

Cover Image

Peripheral Arterial Disease: Interview With Dr James M. Grichnik

By James M. Grichnik, MD, PhD

20:12

Cover Image

The Rational Clinical Examination: David L. Simel, MD, explains the origin and development of The Rational Clinical Examination series and the value of this resource to learners and instructors.

By David L. Simel, MD

15:32

Cover Image

Low Back Pain: Richard A. Deyo, MD, MPH, discusses the clinical examination for low back pain.

By Richard A. Deyo

9:15

Cover Image

Osteoporosis: Cathleen Colón-Emeric, MD, MHSc, MD, MPH, discusses the clinical examination for osteoporosis.

By Cathleen Colón-Emeric, MD, MHSc, MD, MPH

7:26

Cover Image

Urinary Tract Infection, Women: Stephen Bent, MD, discusses the clinical examination for urinary tract infections in women.

By Stephen Bent, MD

6:50

Cover Image

Otitis Media, Child: Russell Rothman, MD, discusses the clinical examination for otitis media in children.

By Russell Rothman, MD

5:34

Cover Image

Influenza: Lauren Brett Caram, MD, discusses the clinical examination for influenza.

By Lauren Brett Caram, MD

9:54

Cover Image

Abdominal Aortic Aneurysm: Frank Lederle, MD, discusses the clinical examination for abdominal aortic aneurysm.

By Frank Lederle, MD,

4:09

Cover Image

Dementia: Tracey Holsinger, MD, discusses the clinical examination for dementia.

By Tracey Holsinger, MD

6:17

Cover Image

Adult Meningitis: Rose Hatala, MD, MSc, discusses the clinical examination for adult meningitis.

By Rose Hatala, MD, MSc

5:54

Cover Image

Heart Failure: Bob Badgett, MD, discusses the clinical examination for heart failure.

By Bob Badgett, MD,

14:56

Cover Image

Knee Ligaments and Menisci: Jeffrey Katz, MD, MSc, and Jonathan Schaffer, MD, MBA, discuss the clinical examination for diagnosing injuries to knee ligaments and menisci.

By Jeffrey Katz, MD, MSc and Jonathan Schaffer, MD, MBA

14:24

Cover Image

Splenomegaly: David L. Simel, MD, MHS, discusses the clinical examination for splenomegaly. Please refer to Figure 46-1 and Figure 46-2 from The Rational Clinical Examination when listening to this podcast.

By David L. Simel, MD, MHS

8:48

Cover Image

Pulmonary Embolism: Jeffrey Ginsberg, MD, FRCPC, discusses the clinical examination for pulmonary embolism.

By Jeffrey Ginsberg, MD, FRCPC

10:03

Cover Image

Adult Appendicitis: James M. Wagner, MD, discusses the clinical examination for adult appendicitis.

By James M. Wagner, MD

12:15

Cover Image

Deep Vein Thrombosis: Philip S. Wells, MD, MSc, discusses the clinical examination for deep vein thrombosis.

By Philip S. Wells, MD, MSc

9:10

Cover Image

Cardiac Tamponade: Niteesh K. Choudhry, MD, PhD, discusses the clinical examination for cardiac tamponade.

By Niteesh K. Choudhry, MD, PhD

8:52

Cover Image

Acute Cholecystitis: Robert L. Trowbridge, MD, discusses the clinical examination for acute cholecystitis.

By Robert L. Trowbridge, MD

5:25

Cover Image

Myocardial Infarction: Akbar A. Panju, MBChB, FRCPC, discusses the clinical examination for myocardial infarction.

By Akbar A. Panju, MBChB, FRCPC

9:55

Cover Image

Hepatomegaly: David L. Simel, MD, MHS, discusses the clinical examination for hepatomegaly.

By David L. Simel, MD, MHS

6:59

Cover Image

Menopause: Lori A. Bastian, MD, MPH, discusses the clinical examination for menopause and perimenopause.

By Lori A. Bastian, MD, MPH

13:03

Cover Image

Murmur, Systolic: Edward Etchells, MD, discusses the clinical examination for systolic murmurs.

By Edward Etchells, MD

8:28

Cover Image

Goiter: Karen Barnard, MD, MPH, discusses the clinical exam for goiters.

By Karen Barnard, MD, MPH

4:51

Cover Image

Breast Cancer: Mary B. Barton, MD, MPP, discusses the clinical examination for breast cancer.

By Mary B. Barton, MD, MPP

10:13

Cover Image

Confidence Intervals: Gordon Guyatt, MD, discusses confidence intervals.

By Gordon Guyatt, MD

15:56

Cover Image

Carotid Bruits: David L. Simel, MD, MHS, discusses the clinical examination for carotid bruits.

By David L. Simel, MD, MHS

9:19

Cover Image

Airflow Limitation: David L. Simel, MD, MHS, discusses the clinical examination for airflow limitation.

By David L. Simel, MD, MHS

7:14

Cover Image

Ascites: John W. Williams, Jr, MD, MHS, discusses the clinical examination for ascites.

By John W. Williams, Jr, MD, MHS

9:07

Cover Image

Carpal Tunnel Syndrome: Richard S. Bedlack, MD, PhD, MS discusses the clinical examination for carpal tunnel syndrome.

By Richard S. Bedlack, MD, PhD, MS

5:19

Cover Image

Clubbing: Kathryn A. Myers, MD, EdM, FRCPC, discusses the clinical examination for clubbing.

By Kathryn A. Myers, MD, EdM, FRCPC

9:38

Cover Image

Sinusitis: John W. Williams, Jr, MD, MHS, discusses the clinical examination for sinusitis.

By John W. Williams, Jr, MD, MHS

7:02

Cover Image

Abdominal Bruits: Sheri A. Keitz, MD, PhD, discusses the clinical examination for abdominal bruits.

By Sheri A. Keitz, MD, PhD

10:21

Cover Image

New! Jerome I. Rotter, MD, discusses genome-wide association studies.

By Jerome I. Rotter, MD

23:25

Cover Image

New! Benjamin R. Saville, PhD, discusses conditional power and determining the likelihood of trial success.

By Benjamin R. Saville, PhD

16:27

Cover Image

Anna E. McGlothlin, PhD, discusses bayesian hierarchical models.

By Anna E. McGlothlin, PhD

15:06

Cover Image

Kelley Kidwell, PhD, discusses SMART designs for randomized trials.

By Kelley A. Kidwell, PhD

13:26

Cover Image

Miguel A. Hernán, MD, DrPH, discusses target trial emulation.

By Miguel A. Hernán, MD, DrPH

27:24

Cover Image

Lawrence Carin, PhD, discusses deep learning for medical image analysis.

By Lawrence Carin, PhD

22:53

Cover Image

Kevin P. Weinfurt, PhD, and Bryce B. Reeve, PhD, discuss patient-reported outcome measures in clinical research.

By Kevin P. Weinfurt, PhD

22:10

Cover Image

Kabir Yadav, MDCM, MS, MSHS, discusses immortal time bias in observational studies.

By Kabir Yadav, MDCM, MS, MSHS

15:06

Cover Image

Lars W. Andersen, MD, MPH, PhD, DMSc, discusses adjustment for baseline characteristics in randomized clinical trials.

By Lars W. Andersen, MD, MPH, PhD, DMSc

18:14

Cover Image

Edward C. Norton, PhD, discusses the correct usage of odds ratios in the clinical literature.

By Edward C. Norton, PhD

12:18

Cover Image

Roderick J. Little, PhD, discusses estimands, estimators, and estimates.

By Roderick J. Little, PhD

22:06

Cover Image

Valerie A. Smith, DrPH, discusses how to interpret the results of intention-to-treat, per-protocol, and as-treated analyses.

By Valerie A. Smith, DrPH

18:26

Cover Image

Juliana Tolles, MD, MHS, discusses time-to-event analysis.

By Juliana Tolles, MD, MHS

11:19

Cover Image

Amanda I. Adler, MD, PhD, and Nicholas Latimer, PhD, discuss adjusting for nonadherence or stopping treatments in randomized clinical trials.

By Amanda I. Adler, MD, PhD, and Nicholas Latimer, PhD

17:59

Cover Image

John M. Lachin, ScD, discusses the worst-rank score methods approach to informatively missing data.

By John M. Lachin, ScD

17:06

Cover Image

Heather G. Allore, PhD, MS, FGSA, discusses the use of latent class analysis to identify hidden clinical phenotypes.

By Heather G. Allore, PhD, MS, FGSA

17:36

Cover Image

Jane Armitage, MBBS, discusses the use of run-in periods in randomized trials.

By Jane Armitage, MBBS

19:28

Cover Image

Matthew L. Maciejewski, PhD, discusses regression discontinuity design.

By Matthew L. Maciejewski, PhD

17:56

Cover Image

Telba Z. Irony, PhD, discusses case-control studies.

By Telba Z. Irony, PhD

23:07

Cover Image

Alex John London, PhD, discusses equipoise in research.

By John London, PhD

21:47

Cover Image

Bayesian Analysis: Using Prior Information to Interpret the Results of Clinical Trials: Audio Interview With Melanie Quintana, PhD

By Melanie Quintana, PhD

27:30

Cover Image

Gillian Sanders-Schmidler, PhD, provides an overview of cost-effectiveness analysis and how it is used to compare the relative costs, benefits, and harms of 2 or more interventions.

By Gillian Sanders-Schmidler, PhD

18:20

Cover Image

Jing Cao, PhD, discusses multiple comparison procedures.

By Jing Cao, PhD

22:46

Cover Image

William J. Meurer, MD, MS, and Juliana Tolles, MD, MHS, discuss the use of logistic regression model diagnostics to determine how well a model predicts outcomes.

By William J. Meurer, MD, MS, and Juliana Tolles, MD, MHS

32:47

Cover Image

Roger J. Lewis, MD, PhD, discusses randomization in clinical trials, specifically in regards to permuted blocks and stratification.

By Roger J. Lewis, MD, PhD

23:13

Cover Image

Susan S. Ellenberg, PhD, discusses stepped-wedge clinical trials and evaluation by rolling deployment.

By Susan S. Ellenberg, PhD

18:06

Cover Image

Anna E. McGlothlin, PhD, discusses minimal clinically important difference and defining what really matters to patients.

By Anna E. McGlothlin, PhD

11:42

Cover Image

Lynne Stokes, PhD, discusses sample size calculation for a hypothesis test.

By Lynn Stokes, PhD

12:13

Cover Image

Harold C. Sox, MD, discusses pragmatic trials and how they can help address “real world” questions.

By Harold C. Sox, MD

21:17

Cover Image

William J. Meurer, MD, MS, discusses cluster randomized trials and evaluating treatments applied to groups.

By William J. Meurer, MD, MS

23:41

Cover Image

Kert Viele, PhD, discusses dose-finding trials and optimizing phase 2 data in the drug development process.

By Kert Viele, PhD

5:04

Cover Image

Amy H. Kaji, MD, PhD, discusses noninferiority trials.

By Amy H. Kaji, MD, PhD

10:52

Cover Image

Edward H. Livingston, MD, and Roger J. Lewis, MD, PhD, discuss the new JAMA Guide to Statistics and Methods book.

By Edward H. Livingston, MD

13:42

Cover Image

Joanne Lynn, MD, MS, discusses the role of hospice and other services.

By Joanne Lynn, MD, MS

37:41

Cover Image

Margot B. Kushel, MD, discusses end-of-life care for homeless patients.

By Margot B. Kushel, MD

22:52

Cover Image

Paul B. Bascom, MD, discusses responding to requests for physician-assisted suicide.

By Paul B. Bascom, MD

15:49

Cover Image

Daniel P. Sulmasy, OFM, MD, PhD, discusses spiritual issues in the care of dying patients.

By Daniel P. Sulmasy, OFM, MD, PhD

25:24

Cover Image

Joshua M. Hauser, MD, discusses physician opportunities to support family caregivers at the end of life.

By Joshua M. Hauser, MD

25:12

Cover Image

Harvey Max Chochinov, MD, PhD, FRSC, discusses dignity-conserving care at the end of life.

By Harvey Max Chochinov, MD, PhD, FRSC

22:25

Cover Image

Psychological Considerations, Growth, and Transcendence at the End Of Life: Interview With Susan D. Block, MD

By Susan D. Block, MD

24:57

Cover Image

James Hallenbeck, MD, discusses palliative care in the final days of life.

By James Hallenbeck, MD

22:56

Cover Image

Sarah E. Harrington, MD, discusses the role of chemotherapy at the end of life.

By Harrington Sarah E., MD

16:07

Cover Image

Sudden Traumatic Death in Children: Interview With Elaine C. Meyer

By Elaine C. Meyer, PhD, RN

36:48

Cover Image

Caring for the Child With Cancer at the Close of Life

By Craig Hurwitz, MD

19:46

Cover Image

Palliative Care for Patients With Head and Neck Cancer: Interview With Dr Nathan E. Goldstein

By Nathan E. Goldstein, MD

15:02

Cover Image

Nathan E. Goldstein, MD, discusses how to talk to patients with limited life expectancy.

By Dr Nathan E. Goldstein and Dr Edward Livingston

26:53

Cover Image

Elizabeth B. Lamont, MD, MS, discusses complexities in prognostication in advanced cancer.

By Dr Elizabeth B. Lamont and Dr Edward Livingston

29:05

Cover Image

Hiroshi Mitsumoto, MD, DSc, discusses palliative care for patients with amyotrophic lateral sclerosis.

By Dr Hiroshi Mitsumoto and Dr Edward Livingston

10:31

Cover Image

Overcoming the False Dichotomy of Curative vs. Palliative Care for Late-Stage HIV/AIDS: Peter A. Selwyn, MD, MPH, discusses the false dichotomy of curative vs palliative care for late-stage HIV/AIDS.

By Peter A. Selwyn, MD, MPH

10:45

Cover Image

Practical Considerations in Dialysis Withdrawal: Lewis M. Cohen, MD, discusses practical considerations in dialysis withdrawal.

By Lewis M. Cohen, MD

6:45

Cover Image

Palliative Care for Patients With Heart Failure: Steven Z. Pantilat, MD, discusses palliative care for patients with heart failure.

By Steven Z. Pantilat, MD

13:04

Cover Image

Care at the Close of Life: Stephen J. McPhee, MD, and Margaret A. Winker, MD, discuss the new JAMAevidence book Care at the Close of Life: Evidence and Experience. Please refer to the JAMA Patient Page on palliative care when listening to this podcast.

By Stephen J. McPhee, MD and Margaret A. Winker, MD

14:09

Cover Image

Initiating End-of-Life Discussions: Timothy E. Quill, MD, discusses initiating end-of-life discussions with seriously ill patients.

By Timothy E. Quill, MD

7:58

Cover Image

Beyond Advance Directives: James A. Tulsky, MD, discusses moving beyond advance directives when communicating with patients at the end of life.

By James A. Tulsky, MD

8:50

Cover Image

Decision Making: Stephen J. McPhee, MD, discusses decision making at a time of crisis near the end of life.

By Stephen J. McPhee, MD

12:58

Cover Image

Conflict: Anthony L. Back, MD, discusses dealing with conflict in caring for the seriously ill.

By Anthony L. Back, MD

14:50

Cover Image

Acute Pain Crisis: Natalie Moryl, MD, discusses managing an acute pain crisis in a patient with advanced cancer.

By Natalie Moryl, MD

6:35

Cover Image

Dyspnea: John M. Luce, MD, discusses management of dyspnea in patients with far-advanced lung disease.

By John M. Luce, MD

5:15

Cover Image

Intractable Nausea and Vomiting: Gordon J. Wood, MD, discusses the management of intractable nausea and vomiting in patients at the end of life.

By Gordon J. Wood, MD

12:04

Cover Image

Palliative Care for Frail Older Adults: Kenneth S. Boockvar, MD, MS, discusses palliative care for frail older adults.

By Kenneth S. Boockvar, MD, MS

11:00

Cover Image

Fatigue: Eduardo Bruera, MD, discusses palliative management of fatigue at the close of life.

By Eduardo Bruera, MD

8:32

Cover Image

Advanced Metastatic Cancer: Janet L. Abrahm, MD, discusses spinal cord compression in patients with advanced metastatic cancer.

By Janet L. Abrahm, MD

11:22

Cover Image

Agitation and Delirium: William Breitbart, MD, discusses agitation and delirium at the end of life.

By William Breitbart, MD

13:35

Cover Image

Alzheimer disease: Ann C. Hurley, RN, DNSc, discusses Alzheimer disease.

By Ann C. Hurley, RN, DNSc

14:50

What is an audio podcast?

An audio podcast is an episodic program delivered via the Internet using an XML protocol called RSS. The publisher podcasts the program by posting the episodes and the XML document to a Web server. The consumer subscribes to the podcast using a client application, such as iTunes, which regularly reads the XML file and downloads new episodes.

Podcasts are attractive to subscribers:

Podcasts are free.
New podcast episodes appear automatically and can be enjoyed anywhere, anytime.

How can I get started?

To subscribe to JAMAevidence podcasts, click on the subscribe link at the top of this page.

If you do not have iTunes, download the latest version of iTunes, free.

How do podcasts work?

Podcasts consist of the episode files that you download and an XML file that lists all the episodes. When you subscribe to a podcast, iTunes reads the XML file and downloads the latest episode. Each day, iTunes rereads the XML file. If a new episode is available, iTunes downloads it automatically.

How does iTunes support podcasts?

The iTunes client application that you download and run on your Mac or PC allows you to subscribe to podcasts and listen to or watch the episodes on your computer, iPod, iPhone, iPad or Apple TV.

The iTunes Store, which includes a podcast directory, helps you find and subscribe to programs and helps podcasters publicize their programs.

Do I need an iPod, iPhone or iPad?

No. Although you can download podcasts to your iPod, iPhone or iPad to play them on the go, you can listen to or watch podcasts on your computer using iTunes or on your TV with Apple TV.

How do I unsubscribe?

If you are no longer interested in a podcast to which you are subscribed, highlight the podcast in your Library and click the Unsubscribe button in the lower lefthand corner of the screen. To unsubscribe and delete all files related to the podcast, simply press the Delete key after selecting a podcast.